Genetic Markers in Duodenal Ulcer Disease

Genetic markers and duodenal ulcer.

Serum pepsinogen, alpha 1-antitrypsin (alpha 1-AT) and blood groups were studied as genetic markers in 32 patients with endoscopically proven duodenal ulcer and 44 control subjects with no family history of ulcer disease. Serum pepsinogen was determined by the modified method of Edward et al, alpha 1-AT by single radial immunodiffusion (RID) and phenotyping was carried out by isoelectric focusi...

Duodenal ulcer in sickle cell disease.

Duodenal Ulcer

hardly possible, but all this has been changed by the aggression of surgery in the field of the physician; happily changed, for though postmortem records of duodenal ulcers were common enough it was not until 1883 that Chvostec for the first time made a diagnosis verified at autopsy. Cordivilla of Bologna inaugurated the surgery of chronic duodenal ulcer in 1893 when he successfully operated on...

Duodenal Ulcer

tion we protested against the surgical arrogance which dogmatically affirmed that hyperchlorhydria is the medical term for the surgical condition, duodenal ulcer, and we are glad to note that the author has so far altered the expression of his view as to inform us that by hyperchlorhydria he means the clinical symptom complex included by physicians under the term, not the mere chemical fact of ...

Duodenal Ulcer in Children

Robb, J. D. A., Thomas, P. S., Orszulok, J., and Odling-Smee, G. W. (1972). Archives ofDisease in Childhood, 47, 688. Duodenal ulcer in children. Forty-nine cases of duodenal ulcer in children are presented. Strict radiological and clinical criteria were observed in making this diagnosis. The children came from a population of approximately 100,000 children over a 10-year period. Upper abdomina...